ONOLIDINE - AN OVERVIEW

Finally, clonidine enhances neuraxial opioids and, in combination with fentanyl, interacts in an additive manner, which might reduce the dose of each part by 60% for postoperative analgesia.Clonidine treats large blood pressure by stimulating α2 receptors from the brainstem, which decreases peripheral vascular resistance, decreasing hypertension.